Ginkgo Biloba For Treating Mild Cognitive Impairment & Dementia

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Scientific research has concluded that there is clear evidence to support the efficacy of the herb Ginkgo Biloba for improving mild cognitive impairment and dementia.

Currently, more than 46 million people live with dementia worldwide, and the number is estimated to increase to 131.5 million by 2050 (Prince et al., 2015). Dementia also has a huge economic impact.

Ginkgo Biloba is a popular herb with a long history of use as a traditional medicine and herbalists often recommend Ginkgo Biloba for improving brain health and cognitive function, preventing dementia, headache, tinnitus, vertigo, mood disturbances, increasing circulation, cardiovascular diseases, and coronary heart disease.

The active components of Ginkgo Biloba include flavonoids, terpene lactones, and ginkgolic acids.

Flavonoids are phyto-nutrients with potent antioxidant and anti-inflammatory properties, which help to combat oxidative stress and inflammation.  Oxidative stress and inflammation are both proven factors in the development of neurodegenerative diseases such as Alzheimer’s.

Ginkgo biloba extracts have been demonstrated to have antioxidative activities, to increase tolerance to hypoxia, and to improve blood rheology by increasing the flexibility of cellular blood components, thus enhancing microcirculation; affecting neurotransmitter levels; enhancing neuroplasticity; prevention of brain edema; and neuroprotection. [1]

Here we will take a look at some of the highlights from the latest scientific research on Ginkgo Biloba for improving cognitive function and treating dementia.

A systematic review published in 2016 evaluated all systematic reviews of Ginkgo Biloba Extracts for prevention of cognitive decline, and intervention of mild cognitive impairment (MCI) and dementia.

The systematic review of the literature concluded:

Our analysis supports the efficacy of Ginkgo Biloba Extract for MCI and dementia of both the Alzheimer type and the vascular type of dementia, and of mixed dementias. In addition, GBEs are generally safe.

An even more current systematic review from 2017 published in the Journal of Ethnopharmacology assessed the cumulative evidence on the efficacy and effectiveness of Ginkgo biloba extract (GbE) in the treatment of dementia.

The systematic review concluded:

Ginkgo Biloba Extract has potentially beneficial effects for people with dementia when it is administered at doses greater than 200mg/day for at least 5 months. Given the lower quality of the evidence, further rigorously-designed, multicenter-based, large-scale RCTs are warranted.

Always consult with a qualified healthcare professional before taking any herbs or dietary supplements.

References

[1] An Overview of Systematic Reviews of Ginkgo biloba Extracts for Mild Cognitive Impairment and Dementia

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138224/

[2] Effects of Ginkgo biloba on dementia: An overview of systematic reviews.

https://www.ncbi.nlm.nih.gov/pubmed/27940086

The information in this article has not been evaluated by the FDA and should not be used to diagnose, cure or treat any disease, implied or otherwise.

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